The difference in fur VS hair is that fur is often much thicker and will hold onto the dander; it gets trapped in the coat. With the Maltipoo, the hair is silky and soft, which allows the dander to fall off. When a person pets a dog or grooms
him, he/she will come into contact with the allergen that is present on the coat. So, with a Maltipoo, much less dander has collected on the coat and a person may have a lowered allergenic response when touching or handling the dog.
Additionally, breeds with fur often have heavy sheds.
This means that the fur (which is holding dander) sheds onto the furniture, flooring, beds and essentially all over the house. Some breeds shed so much that clumps of fur can be found everywhere. The Maltipoo, however, sheds very lightly which means that there will be less dead hairs in the house and on grooming tools, which in turn leads to less allergic responses.
While some refer to the Maltipoo (and its parents, the Poodle and Maltese) and non-shedders, this is not entirely accurate. The coat, as like the skin, is also in a constant state of renewal. Each hair of the Maltipoo's coat is either at growth, rest or fall-out. The difference is that this happens at a much slower rate than dogs with fur.
Therefore, all dogs regardless of type of coat have dander and are, in turn, able to cause an allergic reaction in people who have sensitivity to the dander. The Maltipoo or any other breed with hair is not 100% hypoallergenic. It is more accurate to say that the Maltipoo is low-allergenic.